Purpose: To describe changes in the side-effects associated with chemotherapy for induction of remission of patients with acute myelocytic leukemia.
Method: Nursing recordings, admission notes, chemotherapy side-effects recording sheets, and I oratory sheets of 45 patients with AML who admitted to LAF room at one university hospital from July, 1998 to January, 2002 and received chemotherapy for induction of remission were analyzed retrospectively. Each mean of 6 side-effects(nausea, vomiting, diarrhea, fever, stomatitis, and WBC count) were surveied daily from the first day to 28th day of chemotherapy.
Result: The nausea and vomiting were the most severe at the 5th, 6th day of chemotherapy. The severity of diarrhea was increased from the 7th day and achieved the highest at the 10th and 11th day. The fever was the most severe at the 8th day and decreased after the 22th day. The severity of stomatitis was increased from the 8th day and achieved the highest at the 17th day. The WBC count was 411/㎣, the lowest, at the 13th day and 1,030/㎣ at the 21th day.
Conclusion: The side-effects of patients changed during treatment. Then, nurses must provide seasonable interventions to the changes of each side-effect.
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